The first wrinkle injections made by scientists were from purified collagen taken from cows, for the most part. While it offered an organic fill and worked well, the results didn’t last quite that long. Most collagen fills only last about one month before a patient may start to notice breaks, and as they come from an animal, collagen wrinkle injections also have an increased rate of an allergic reaction. Some patients may actually need to be tested before they undergo treatment, just in case.
Interestingly enough, new ways of producing synthetic versions of this filler are making these types of wrinkle injections safer, so that a wide variety of people can use them. While the results don’t last that long, they do offer a more natural look. Collagen injections also have the typical complications that come with most wrinkle injections, like redness and bruising.